This case study describes the process and experience of establishing a maggot therapy programme in Kenya. Initially, the programme included a technology- and knowledge-transfer initiative which successfully developed production capacity and clinical skills among the surgical and nursing workforce at Kenyatta National Hospital. This work was followed by a pilot study that demonstrated the positive impact mainstreaming of maggot therapy can have on the treatment of patients with chronic and infected wounds. The project highlights the importance of regulatory and supply-chain barriers that need to be addressed from the outset when introducing maggot therapy to new markets.